Karen is Marzipan's cousin. She is a sales representative for Pyramax, a "work-from-home" MLM scheme that, like Bubs' Concession Stand, sells a lot of often unusual things. She is also an anti-vaxxer and a essential oils fangirl. Like The Infowarrior, she is hated by everybody else in Free Country, USA, even her own cousin.
She is inspired by the Reddit meme "Karen", often used to mock anti-vaxxer moms and/or females involved in MLM schemes.